Article

Exome sequencing and genotyping identify a rare variant in <i>NLRP7</i> gene associated with ulcerative colitis

2017-08-29

Abstract excerpt

<h4>Background and aims</h4> Although genome-wide association studies (GWAS) in inflammatory bowel disease (IBD) have identified a large number of common disease susceptibility alleles for both Crohn’s disease (CD) and ulcerative colitis (UC), a substantial fraction of IBD heritability remains unexplained, suggesting that rare coding genetic variants may also have a role in pathogenesis. We used high-throughput s...

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Literature Corpus work: b92aca46-aae7-55e2-ac8a-a762f14be400
DOI: 10.1101/182113

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