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Article

Vitamin D and Inflammatory Bowel Disease: Mendelian Randomization Analyses in the Copenhagen Studies and UK Biobank.

The Journal of clinical endocrinology and metabolism - 1 Sept 2018

Lund-Nielsen Josephine, Vedel-Krogh Signe, Kobylecki Camilla Jannie, Brynskov Jørn, Afzal Shoaib, Nordestgaard Børge G

Abstract excerpt

Context: Vitamin D may be a modifiable risk factor for inflammatory bowel disease (IBD). Objectives: We tested the hypothesis that plasma 25-hydroxyvitamin D levels are causally associated with risk of Crohn disease (CD) and ulcerative colitis (UC). Design, Setting, Patients, and Interventions: We used a Mendelian randomization design to study 120,013 individuals from the Copenhagen City Heart Study, the...

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Identifiers

PMID: 29947775
DOI: 10.1210/jc.2018-00250

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DHCR7

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