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Article

Genomic determinants of normal tissue toxicity after radiotherapy for head and neck malignancy: a systematic review.

Oral oncology - 1 Nov 2012

Ghazali Naseem, Shaw Richard J, Rogers Simon N, Risk Janet M

Abstract excerpt

Interindividual variations in radiotoxicity responses exist despite uniform treatment protocols. It is speculated that normal genetic variants, particularly single nucleotide polymorphisms (SNPs) may influence normal head and neck (HN) tissue radiotoxicity. This first-ever systematic review was undertaken to evaluate the association of SNPs with normal HN tissues radiotoxicity. Multiple databases (1950-February...

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Identifiers

PMID: 22939215
DOI: 10.1016/j.oraloncology.2012.08.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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