Article
NOD2/CARD15 gene polymorphisms in idiopathic pulmonary fibrosis.
Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG - 1 Oct 2005
Zorzetto Michele, Ferrarotti Ilaria, Campo Ilaria, Trisolini Rocco, Poletti Venerino, Scabini Roberta, Ceruti Michele, Mazzola Paola, Crippa Elena, Ottaviani Stefania, Agostini Carlo, Semenzato Gianpietro, Pozzi Ernesto, Luisetti Maurizio
Abstract excerpt
BACKGROUND: Micro-organisms, behaving in a non-infectious fashion, may be among the exogenous factor(s) believed to trigger idiopathic pulmonary fibrosis (IPF). One possible strategy to identify an individual's susceptibility to such microbial triggers, which are likely to be ubiquitous, is to investigate the molecular processes involved in their recognition. NOD2/CARD15 is a specific pattern recognition receptor...
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