Article
Influence of polymorphisms in the NOD1/CARD4 and NOD2/CARD15 genes on the clinical outcome of Helicobacter pylori infection.
Cellular microbiology - 1 Jul 2006
Rosenstiel Philip, Hellmig Stephan, Hampe Jochen, Ott Stefan, Till Andreas, Fischbach Wolfgang, Sahly Hany, Lucius Ralph, Fölsch Ulrich R, Philpott Dana, Schreiber Stefan
Abstract excerpt
Host immune response influences the clinical outcome of Helicobacter pylori infection leading to ulcer disease, gastric carcinoma and mucosa-associated lymphoid tissue (MALT) lymphoma. A genetic risk profile for gastric cancer has been identified, but genetic susceptibility to develop MALT lymphoma is still unclear. We investigated the role of NOD1 and NOD2 as intracellular recognition molecules for...
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