Article
Impact of reduced levels of APE1 transcripts on the survival of patients with urothelial carcinoma of the bladder.
Oncology reports - 1 Oct 2015
Chantre-Justino Mariana, Alves Gilda, Britto Constança, Cardoso Angélica, Scherrer Luciano, Moreira Aline dos Santos, Quirino Raul, Ornellas Antonio, Leitão Alvaro, Lage Claudia
Abstract excerpt
Molecular evidence indicates that alterations in genes involved in the maintenance of genome stability may be related to susceptibility to bladder carcinoma. Our goal was to evaluate the prognostic role of base excision repair (BER) genes in a cohort of patients diagnosed with primary urothelial carcinoma of the bladder (UCB). The levels of all APE1, XRCC1 and POLB transcripts were detected by quantitative...
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