Article
Base excision repair genes XRCC1 and APEX1 and the risk for prostate cancer.
Molecular biology reports - 1 Mar 2011
Kuasne H, Rodrigues I S, Losi-Guembarovski R, Reis M B, Fuganti P E, Gregório E P, Libos Junior F, Matsuda H M, Rodrigues M A F, Kishima M O, Cólus I M S
Abstract excerpt
Prostate cancer is the second cause of cancer death in Brazilian men. One of the relevant phenomena to the inherited susceptibility is the presence of allelic variants in genes involved with the DNA repair pathway. The aim of this study was to analyze the frequencies of prevalent, heterozygous and rare genotypes of the base excision repair genes APEX1 and XRCC1 in a case-control study and relate the genotypes...
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