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Article

The heat shock response restricts virus infection in Drosophila

3 Aug 2015

Abstract excerpt

Innate immunity is the first line of defence against pathogens and is essential for survival of the infected host. The fruit fly Drosophila melanogaster is an emerging model to study viral pathogenesis, yet antiviral defence responses remain poorly understood. Here, we describe the heat shock response, a cellular mechanism that prevents proteotoxicity, as a component of the antiviral immune response in...

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PMID: 26234525
DOI: 10.1038/srep12758

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