The Hsf1-sHsp cascade has pan-antiviral activity in mosquito cells

Abstract excerpt

Aedes mosquitoes transmit pathogenic arthropod-borne (arbo) viruses, putting nearly half the world's population at risk. Blocking virus replication in mosquitoes is a promising approach to prevent arbovirus transmission, the development of which requires in-depth knowledge of virus-host interactions and mosquito immunity. By integrating multi-omics data, we find that heat shock factor 1 (Hsf1) regulates eight...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Heat shock proteins research
• Share to Mosquito-borne diseases and control
• Share to Viral Infections and Vectors