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Article

Age-dependent impairment of disease tolerance is associated with a robust transcriptional response following RNA virus infection in <i>Drosophila</i>

2020-09-21

Abstract excerpt

<h4>Summary</h4> Advanced age in humans is associated with greater susceptibility to and higher mortality rates from infections, including infections with some RNA viruses. The underlying innate immune mechanisms, which represent the first line of defense against pathogens, remain incompletely understood. Drosophila melanogaster is able to mount potent and evolutionarily conserved innate immune defenses against...

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Literature Corpus work
a80667e5-835a-553e-a14b-824118ed998b
DOI
10.1101/2020.09.21.307017
Open publication

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Age-dependent impairment of disease tolerance is associated with a robust transcriptional response following RNA virus infection in <i>Drosophila</i>DOI 10.1101/2020.09.21.307017
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