Article

The Hsf1-sHsp cascade has pan-antiviral activity in mosquito cells

2023-02-21

Abstract excerpt

Aedes mosquitoes transmit pathogenic arthropod-borne (arbo) viruses, putting nearly half the world's population at risk. Blocking virus replication in mosquitoes is a promising approach to prevent arbovirus transmission, the development of which requires in-depth knowledge of virus-host interactions and mosquito immunity. By integrating multi-omics data, we find that heat shock factor 1 (Hsf1) regulates eight smal...

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Literature Corpus work: 5e3f6b21-3972-5723-918f-0d1a8e51673f
DOI: 10.1101/2023.02.21.529413

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