Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional characterization of CYP1A9 and CYP1C1 from Anguillus japonica.

Environmental toxicology and pharmacology - 1 Sept 2015

Uno Tomohide, Izumi Chiho, Takenaka Shinji, Yanase Takeshi, Imaishi Hiromasa, Kanamaru Kengo, Yamagata Hiroshi, Kaminishi Yoshio, Itakura Takao

Abstract excerpt

We evaluated the metabolism of several herbicides and progesterone by two P450 proteins (CYP1A9 and CYP1C1) from Japanese eel (Anguilla japonica). Expression vectors harboring CYP1A9 and CYP1C1 sequences were introduced into Escherichia coli. E. coli membrane fractions were incubated with each substrate, and the metabolites were analyzed. CYP1A9 and CYP1C1 deethylated 7-ethoxycoumarin and phenacetin, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Binding Sites
Share to Coumarins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 Enzyme System

Share to Escherichia coli

Share to Fish Proteins

Share to Mutation

Share to Progesterone

Share to Substrate Specificity

Source

Identifiers

PMID: 26233561
DOI: 10.1016/j.etap.2015.07.006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional characterization of CYP1A9 and CYP1C1 from Anguillus japonica.PMID 26233561Read ↗

Important amino acid residues that confer CYP2C19 selective activity to CYP2C9.Semantic proximity Read ↗

Metabolism of 7-ethoxycoumarin, flavanone and steroids by cytochrome P450 2C9 variants.Semantic proximity Read ↗

Expression of modified human cytochrome P450 1A1 in Escherichia coli: effects of 5' substitution, stabilization, purification, spectral characterization, and catalytic properties.Semantic proximity Read ↗

Metabolism of steroids by cytochrome P450 2C9 variants.Semantic proximity Read ↗

Structure/function relationship of CYP11B1 associated with Dahl's salt-resistant rats--expression of rat CYP11B1 and CYP11B2 in Escherichia coli.Semantic proximity Read ↗

Bioactivity of Curcumin on the Cytochrome P450 Enzymes of the Steroidogenic PathwaySemantic proximity Read ↗

Allelic variants of human cytochrome P450 1A1 (CYP1A1): effect of T461N and I462V substitutions on steroid hydroxylase specificity.Semantic proximity Read ↗

A rational approach to Re-engineer cytochrome P450 2B1 regioselectivity based on the crystal structure of cytochrome P450 2C5.Semantic proximity Read ↗

cDNA-directed expression of two allelic variants of cytochrome P450 2C11 using COS1 and SF21 insect cells.Semantic proximity Read ↗

The role of cytochrome 2B1 substrate recognition site residues 115, 294, 297, 298, and 362 in the oxidation of steroids and 7-alkoxycoumarins.Semantic proximity Read ↗

Catalytic properties of polymorphic human cytochrome P450 1B1 variants.Semantic proximity Read ↗

Specificity of 17beta-oestradiol and benzo[a]pyrene oxidation by polymorphic human cytochrome P4501B1 variants substituted at residues 48, 119 and 432.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.