Structure/function relationship of CYP11B1 associated with Dahl's salt-resistant rats--expression of rat CYP11B1 and CYP11B2 in Escherichia coli.

doi:10.1046/j.1432-1327.1998.2580869.x

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Article

Structure/function relationship of CYP11B1 associated with Dahl's salt-resistant rats--expression of rat CYP11B1 and CYP11B2 in Escherichia coli.

European journal of biochemistry - 1 Dec 1998

Nonaka Y, Fujii T, Kagawa N, Waterman M R, Takemori H, Okamoto M

Abstract excerpt

Dahl's salt-resistant normotensive rats (DR rats) have been previously reported to express cytochrome P-450 (CYP11B1) containing five missense mutations [Matsukawa, N., Nonaka, Y., Higaki, J., Nagano, M., Mikami H., Ogihara, T. & Okamoto, M. (1993) J. Biol. Chem. 268, 9117-9121]. To investigate s...

Topics

Amino Acid Sequence
Animals
Base Sequence
Cytochrome P-450 CYP11B2
DNA Primers
Desoxycorticosterone
Immunoblotting
Molecular Sequence Data
Molecular Structure
Mutation
Polymerase Chain Reaction
Rats
Rats, Inbred Dahl
Recombinant Proteins
Steroid 11-beta-Hydroxylase

Source

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Identifiers

PMID: 9874258
DOI: 10.1046/j.1432-1327.1998.2580869.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9874258-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Steroid Hydroxylases

Steroids

Structure-Activity Relationship