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Article

Catalytic properties of polymorphic human cytochrome P450 1B1 variants.

Carcinogenesis - 1 Aug 1999

Shimada T, Watanabe J, Kawajiri K, Sutter T R, Guengerich F P, Gillam E M, Inoue K

Abstract excerpt

Four polymorphic human cytochrome P450 (CYP) 1B1 allelic variants, namely Arg48,Ala119,Leu432,Asn453, Arg48,Ser119,Leu432,Asn453, Arg48, Ala119,Val432,Asn-453 and Arg48,Ser119,Val432,Asn453, were expressed in Escherichia coli together with human NADPH-P450 reductase and the recombinant proteins (in bacterial membranes) were used to assess whether CYP1B1 polymorphisms affect catalytic activities towards a variety...

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PMID: 10426814
DOI: 10.1093/carcin/20.8.1607

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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