[Relationships between Half-Lives of Dioxins and SNPs in AhR among Yusho Patients].

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[Relationships between Half-Lives of Dioxins and SNPs in AhR among Yusho Patients].

Fukuoka igaku zasshi = Hukuoka acta medica - 1 May 2015

Matsumoto Shinya, Akahane Manabu, Kanagawa Yoshiyuki, Kajiwara Jumboku, Tsukimori Kiyomi, Wake Norio, Mitoma Chikage, Uchi Hiroshi, Furue Masutaka, Imamura Tomoaki

Abstract excerpt

Half-lives of blood levels of 2,3,4,7,8-Pentachlorodibenzofuran (PeCDF) are varied in Yusho patients. The objective was to evaluate a relationship between half-lives of PeCDF levels and types of SNP rs10249788 of aryl hydrocarbon receptor (AHR) gene in 93 Yusho patients. Based on physical symptoms, age, sex, body mass index and other factors, we set up suitable calculation formulas to fit the actual PeCDF levels...

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PMID: 26226675

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