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Article

Genetic susceptibility to dioxin-like chemicals' induction of cytochrome P4501A2 in the human adult linked to specific AhRR polymorphism.

Chemosphere - 1 Mar 2013

Hung Wan-Ting, Lambert George H, Huang Ping-Wei, Patterson Donald G, Guo Yue Leon

Abstract excerpt

BACKGROUND: Dioxin-like chemicals are known to exert their effect by binding to aryl hydrocarbon receptor (AhR), forming complexes with aryl hydrocarbon nuclear translocator (ARNT), and binding to dioxin responsive elements (DREs) in promoter region to regulate the transcription of specific genes. In a previous study of the Yucheng cohort of humans who were exposed to high toxic levels of dioxin-like chemicals...

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Share to Aryl Hydrocarbon Receptor Nuclear Translocator
Share to Cytochrome P-450 CYP1A2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to ARNT gene

Share to Genetic Predisposition to Disease

Share to Polymorphism, Single Nucleotide

Share to Receptors, Aryl Hydrocarbon

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Source

Identifiers

PMID: 23168330
DOI: 10.1016/j.chemosphere.2012.10.026

Genes

ARNT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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