Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human and rodent aryl hydrocarbon receptor (AHR): from mediator of dioxin toxicity to physiologic AHR functions and therapeutic options.

Biological chemistry - 1 Apr 2017

Bock Karl Walter

Abstract excerpt

Metabolism of aryl hydrocarbons and toxicity of dioxins led to the discovery of the aryl hydrocarbon receptor (AHR). Tremendous advances have been made on multiplicity of AHR signaling and identification of endogenous ligands including the tryptophan metabolites FICZ and kynurenine. However, human AHR functions are still poorly understood due to marked species differences as well as cell-type- and cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to AHR gene
Share to Genetic Variation
Share to Homeostasis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Ligands

Share to Receptors, Aryl Hydrocarbon

Share to Rodentia

Share to Signal Transduction

Share to Stem Cells

Source

Identifiers

PMID: 27805907
DOI: 10.1515/hsz-2016-0303

Genes

AHR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human and rodent aryl hydrocarbon receptor (AHR): from mediator of dioxin toxicity to physiologic AHR functions and therapeutic options.PMID 27805907Read ↗

The aryl hydrocarbon receptor in the crossroad of signalling networks with therapeutic value.Semantic proximity Read ↗

Molecular Evolution of Aryl Hydrocarbon Receptor Signaling Pathway GenesSemantic proximity Read ↗

Towards Targeting the Aryl Hydrocarbon Receptor in Cystic FibrosisSemantic proximity Read ↗

The immune phenotype of AhR null mouse mutants: not a simple mirror of xenobiotic receptor over-activation.Semantic proximity Read ↗

Old Receptor, New Tricks—The Ever-Expanding Universe of Aryl Hydrocarbon Receptor Functions. Report from the 4th AHR Meeting, 29–31 August 2018 in Paris, FranceSemantic proximity Read ↗

The aryl hydrocarbon receptor pathway: a linking bridge between the gut microbiome and neurodegenerative diseasesSemantic proximity Read ↗

An in vitro model of human hematopoiesis identifies a regulatory role for the aryl hydrocarbon receptorSemantic proximity Read ↗

The aryl hydrocarbon receptor: Regulation of hematopoiesis and involvement in the progression of blood diseasesSemantic proximity Read ↗

Aryl hydrocarbon receptor (AHR): From selected human target genes and crosstalk with transcription factors to multiple AHR functionsSemantic proximity Read ↗

Environmental exposure and the role of AhR in the tumor microenvironment of breast cancerSemantic proximity Read ↗

Targeting AhR as a Novel Therapeutic Modality against Inflammatory Diseases.Semantic proximity Read ↗

Endogenous functions of the aryl hydrocarbon receptor (AHR): intersection of cytochrome P450 1 (CYP1)-metabolized eicosanoids and AHR biology.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.