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CFAP54 is required for proper ciliary motility and assembly of the central pair apparatus in mice

30 Jul 2015

Abstract excerpt

Motile cilia and flagella play critical roles in fluid clearance and cell motility, and dysfunction commonly results in the pediatric syndrome primary ciliary dyskinesia (PCD). CFAP221, also known as PCDP1, is required for ciliary and flagellar function in mice and Chlamydomonas reinhardtii, where it localizes to the C1d projection of the central microtubule apparatus and functions in a complex that regulates...

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PMID: 26224312
DOI: 10.1091/mbc.e15-02-0121

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