Article
The FOXJ1 target Cfap206 is required for sperm motility, mucociliary clearance of the airways and brain development.
Development (Cambridge, England) - 15 Jun 2020
Beckers Anja, Adis Christian, Schuster-Gossler Karin, Tveriakhina Lena, Ott Tim, Fuhl Franziska, Hegermann Jan, Boldt Karsten, Serth Katrin, Rachev Ev, Alten Leonie, Kremmer Elisabeth, Ueffing Marius, Blum Martin, Gossler Achim
Abstract excerpt
Cilia are complex cellular protrusions consisting of hundreds of proteins. Defects in ciliary structure and function, many of which have not been characterised molecularly, cause ciliopathies: a heterogeneous group of human syndromes. Here, we report on the FOXJ1 target gene Cfap206, orthologues of which so far have only been studied in Chlamydomonas and Tetrahymena In mouse and Xenopus, Cfap206 was co-expressed...
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