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Article

Heat shock factor 1 induces cancer stem cell phenotype in breast cancer cell lines.

Breast cancer research and treatment - 1 Aug 2015

Wang Bin, Lee Chung-Wei, Witt Abigail, Thakkar Ankita, Ince Tan A

Abstract excerpt

Heat shock factor 1 (HSF1) has long been recognized as the master transcription factor that regulates heat shock proteins (HSPs). More recently HSF1 has been associated with a broader role in regulating response to a variety of cellular stresses beyond heat-shock. We previously found that high HSF1 expression is associated with poor outcome in lung, breast and colon cancers. Importantly, however, the HSF1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26223813
DOI: 10.1007/s10549-015-3521-1
PMCID: PMC4536274

Genes

HSF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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