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Article

Cytochrome P450 2C19 polymorphisms and valproic acid-induced weight gain.

Acta neurologica Scandinavica - 1 Mar 2016

Noai M, Soraoka H, Kajiwara A, Tanamachi Y, Oniki K, Nakagawa K, Ishitsu T, Saruwatari J

Abstract excerpt

OBJECTIVES: Cytochrome P450 (CYP) 2C19 plays a role in the biotransformation of clinically relevant drugs as well as endogenous compounds, including sex hormones, which are known to be modulators of food intake and energy balance in humans. We attempted to investigate the influence of CYP2C19 polymorphisms on valproic acid (VPA)-induced weight gain. MATERIALS AND METHODS: This retrospective longitudinal study...

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Identifiers

PMID: 26223287
DOI: 10.1111/ane.12473

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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