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Article

Genetic variant of the histamine-1 receptor (glu349asp) and body weight change during clozapine treatment.

Psychiatric genetics - 1 Sept 2002

Hong Chen-Jee, Lin Ching-Hua, Yu Younger W-Y, Chang Su-Chen, Wang Shu-Ying, Tsai Shih-Jen

Abstract excerpt

Clozapine treatment frequently causes body weight gain that may impair health and may affect patient compliance. While the histamine-1 (H1) receptor may play a major role in the mechanism of the clozapine-induced body weight change, we tested the relationship between the genetic variant (Glu349Asp) of the H1 receptor and the clozapine-induced body weight change. Eighty-eight schizophrenic patients treated with...

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Identifiers

PMID: 12218662
DOI: 10.1097/00041444-200209000-00009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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