Article
Weight change, genetics and antiepileptic drugs.
Expert review of clinical pharmacology - 1 Jan 2014
Chukwu Joseph, Delanty Norman, Webb David, Cavalleri Gianpiero L
Abstract excerpt
Weight gain caused by antiepileptic drugs (AEDs) constitutes a serious problem in the management of people with epilepsy. AEDs associated with weight gain include sodium valproate, pregabalin and vigabatrin. Excessive weight gain can lead to non-compliance with treatment and to an exacerbation of obesity-related conditions. The mechanisms by which AEDs cause weight gain are not fully understood. It is likely that...
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