Article
Genetic variants of the serotonin system and weight change during clozapine treatment.
Pharmacogenetics - 1 Apr 2001
Hong C J, Lin C H, Yu Y W, Yang K H, Tsai S J
Abstract excerpt
Clozapine-induced weight gain may impair health and affect patient compliance. The aim of this study is to investigate the relationship between the genetic variants of the serotonin system and clozapine-induced body weight change (BWC). Ninety-three treatment-resistant schizophrenic patients were weighed monthly for 4 months during clozapine treatment. At the conclusion of treatment, patients had gained an...
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