Article
Lack of association between the -759C/T polymorphism of the 5-HT2C receptor gene and clozapine-induced weight gain among German schizophrenic individuals.
Psychiatric genetics - 1 Sept 2004
Theisen Frank M, Hinney Anke, Brömel Torsten, Heinzel-Gutenbrunner Monika, Martin Matthias, Krieg Jürgen-Christian, Remschmidt Helmut, Hebebrand Johannes
Abstract excerpt
Weight gain is a major side effect of treatment with clozapine and other antipsychotics. Recent studies suggest an important role of the serotonin type 2C receptor gene (5-HT2CR) in antipsychotic-induced weight gain. However, investigations pertaining to a possible association between a -759C/T p...
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