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Article

DC-Based Immunotherapy Combined with Low-Dose Methotrexate Effective in the Treatment of Advanced CIA in Mice.

Journal of immunology research - 1 Jan 2015

Park Jun-Eui, Jang Jinah, Choi Ji-Hye, Kang Mi-Sun, Woo Yun-Ju, Seong Young-Rim, Choi Chan-Bum, Lee Hye-Soon, Bae Sang-Cheol, Bae Yong-Soo

Abstract excerpt

We have previously demonstrated that semimature dendritic cell- (smDC-) based immunotherapy is effective for the treatment of collagen-induced arthritis (CIA) prior to disease onset. In the present study, we examined the efficacy of combination therapy with smDCs and methotrexate (MTX) in advanced CIA with a score of 2-3. Combination therapy with low-dose MTX and type II collagen- (CII-) pulsed smDCs (CII-smDCs)...

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Identifiers

PMID: 26221616
DOI: 10.1155/2015/834085
PMCID: PMC4499408

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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