Article
Identification and Characterization of CD300H, a New Member of the Human CD300 Immunoreceptor Family.
The Journal of biological chemistry - 4 Sept 2015
Niizuma Kouta, Tahara-Hanaoka Satoko, Noguchi Emiko, Shibuya Akira
Abstract excerpt
Recruitment of circulating monocytes and neutrophils to infection sites is essential for host defense against infections. Here, we identified a previously unannotated gene that encodes an immunoglobulin-like receptor, designated CD300H, which is located in the CD300 gene cluster. CD300H has a short cytoplasmic tail and associates with the signaling adaptor proteins, DAP12 and DAP10. CD300H is expressed on CD16(+)...
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