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Article

Common polygenic variation contributes to risk of migraine in the Norfolk Island population.

Human genetics - 1 Oct 2015

Rodriguez-Acevedo A J, Ferreira M A, Benton Miles C, Carless Melanie A, Goring Harald H, Curran Joanne E, Blangero John, Lea R A, Griffiths L R

Abstract excerpt

Migraine has been defined as a common disabling primary headache disorder. Epidemiology studies have provided with the undeniable evidence of genetic components as active players in the development of the disease under a polygenic model in which multiple risk alleles exert modest individual effects. Our objective was to test the contribution of a polygenic effect to migraine risk in the Norfolk Island population...

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PMID: 26220684
DOI: 10.1007/s00439-015-1587-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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