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Article

Variants in the human potassium channel gene (KCNN3) are associated with migraine in a high risk genetic isolate.

The journal of headache and pain - 1 Dec 2011

Cox Hannah C, Lea Rod A, Bellis Claire, Carless Melanie, Dyer Tom, Blangero John, Griffiths Lyn R

Abstract excerpt

The calcium-activated potassium ion channel gene (KCNN3) is located in the vicinity of the familial hemiplegic migraine type 2 locus on chromosome 1q21.3. This gene is expressed in the central nervous system and plays a role in neural excitability. Previous association studies have provided some, although not conclusive, evidence for involvement of this gene in migraine susceptibility. To elucidate KCNN3...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Small-Conductance Calcium-Activated Potassium Channels

Source

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Identifiers

PMID: 22030984
DOI: 10.1007/s10194-011-0392-7
PMCID: PMC3208049

Genes

KCNN3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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