Article
Genetics of migraine: Delineation of contemporary understanding of the genetic underpinning of migraine.
Handbook of clinical neurology - 1 Jan 2023
de Boer Irene, Harder Aster V E, Ferrari Michel D, van den Maagdenberg Arn M J M, Terwindt Gisela M
Abstract excerpt
Migraine is a disabling episodic brain disorder with an increased familial relative risk, an increased concordance in monozygotic twins, and an estimated heritability of approximately 50%. Various genetic approaches have been applied to identify genetic factors conferring migraine risk. Initially, candidate gene associations studies (CGAS) have been performed that test DNA variants in genes prioritized based on...
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