Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An X chromosome association scan of the Norfolk Island genetic isolate provides evidence for a novel migraine susceptibility locus at Xq12.

PloS one - 1 Jan 2012

Maher Bridget H, Lea Rod A, Benton Miles, Cox Hannah C, Bellis Claire, Carless Melanie, Dyer Thomas D, Curran Joanne, Charlesworth Jac C, Buring Julie E, Kurth Tobias, Chasman Daniel I, Ridker Paul M, Schürks Markus, Blangero John, Griffiths Lyn R

Abstract excerpt

Migraine is a common and debilitating neurovascular disorder with a complex envirogenomic aetiology. Numerous studies have demonstrated a preponderance of women affected with migraine and previous pedigree linkage studies in our laboratory have identified susceptibility loci on chromosome Xq24-Xq28. In this study we have used the genetic isolate of Norfolk Island to further analyse the X chromosome for migraine...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Human, X
Share to Genes, X-Linked

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Loci

Share to Genetic Markers

Share to Haplotypes

Share to Melanesia

Share to Migraine Disorders

Share to Reproducibility of Results

Source

Open in PubMed Open full text

Identifiers

PMID: 22666411
DOI: 10.1371/journal.pone.0037903
PMCID: PMC3362572

Genes

HEPH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An X chromosome association scan of the Norfolk Island genetic isolate provides evidence for a novel migraine susceptibility locus at Xq12.PMID 22666411Read ↗

Heritability and genome-wide linkage analysis of migraine in the genetic isolate of Norfolk Island.Semantic proximity Read ↗

A genome-wide analysis of 'Bounty' descendants implicates several novel variants in migraine susceptibility.Semantic proximity Read ↗

Variants in the human potassium channel gene (KCNN3) are associated with migraine in a high risk genetic isolate.Semantic proximity Read ↗

Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine.Semantic proximity Read ↗

Association of oestrogen-receptor gene (ESR1) polymorphisms with migraine in the large Norfolk Island pedigree.Semantic proximity Read ↗

Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraineSemantic proximity Read ↗

A novel locus for familial migraine on Xp22.Semantic proximity Read ↗

Common polygenic variation contributes to risk of migraine in the Norfolk Island population.Semantic proximity Read ↗

Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles.Semantic proximity Read ↗

<i>Neuropeptide S</i> as a potential risk <i>locus</i> for migraine in the Portuguese populationSemantic proximity Read ↗

Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1.Semantic proximity Read ↗

Study of association of migraine susceptibility genes with common migraine in 200,000 exome-sequenced UK Biobank participantsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.