Article
Rare risk variants associate with epigenetic dysregulation in migraine
2021-12-21
Abstract excerpt
<h4>ABSTRACT</h4> Migraine has a heritability of up to 65%. Genome-wide association studies (GWAS) on migraine have identified 123 risk loci, explaining only 10.6% of migraine heritability. Thus, there is a considerable genetic component not identified with GWAS. Further, the causality of the identified risk loci remains inconclusive. Rare variants contribute to the risk of migraine but GWAS are often underpowered...
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Identifiers and source
- Literature Corpus work
- fed6fa26-d722-5883-bbd9-e62a0b372fc7
- DOI
- 10.1101/2021.12.20.21268001