Article
Common variant burden contributes significantly to the familial aggregation of migraine in 1,589 families
2017-11-30
Abstract excerpt
It has long been observed that complex traits, including migraine, often aggregate in families, but the underlying genetic architecture behind this is not well understood. Two competing hypotheses exist, emphasizing either rare or common genetic variation. More specifically, familial aggregation could be predominantly explained by rare, penetrant variants that segregate according to Mendelian inheritance or rather...
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Identifiers and source
- Literature Corpus work
- 2e319ac3-fef9-5cc1-b996-9cc359ff3564
- DOI
- 10.1101/226985