Article
International warfarin genotype-guided dosing algorithms in the Turkish population and their preventive effects on major and life-threatening hemorrhagic events.
Pharmacogenomics - 1 Jan 2015
Karaca Sefayet, Bozkurt Nujen Colak, Cesuroglu Tomris, Karaca Mehmet, Bozkurt Mehmet, Eskioglu Erdal, Polimanti Renato
Abstract excerpt
AIM: To determine the accuracy of international warfarin pharmacogenetic algorithms developed on large multiethnic cohorts (comprising more than 1000 subjects) to predict therapeutic warfarin doses in Turkish patients. MATERIALS & METHODS: We investigated two Turkish warfarin-treated cohorts: patients with no history of hemorrhagic or thromboembolic event and patients with major and life-threatening hemorrhagic...
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