Article
Evaluation of 16 genotype-guided Warfarin Dosing Algorithms in 310 Korean Patients Receiving Warfarin Treatment: Poor Prediction Performance in VKORC1 1173C Carriers.
Clinical therapeutics - 1 Dec 2016
Yang Mina, Choi Rihwa, Kim June Soo, On Young Keun, Bang Oh Young, Cho Hyun-Jung, Lee Soo-Youn
Abstract excerpt
PURPOSE: The purpose of this study was to evaluate the performance of 16 previously published warfarin dosing algorithms in Korean patients. METHODS: The 16 algorithms were selected through a literature search and evaluated using a cohort of 310 Korean patients with atrial fibrillation or cerebral infarction who were receiving warfarin therapy. FINDINGS: A large interindividual variation (up to 11-fold) in...
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