Article
High-throughput sequencing of the synaptome in major depressive disorder.
Molecular psychiatry - 1 May 2016
Pirooznia M, Wang T, Avramopoulos D, Potash J B, Zandi P P, Goes F S
Abstract excerpt
Major depressive disorder (MDD) is among the leading causes of worldwide disability. Despite its significant heritability, large-scale genome-wide association studies (GWASs) of MDD have yet to identify robustly associated common variants. Although increased sample sizes are being amassed for the next wave of GWAS, few studies have as yet focused on rare genetic variants in the study of MDD. We sequenced the...
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