Genetic variants of ACE (Insertion/Deletion) and AGT (M268T) genes in patients with diabetes and nephropathy.

doi:10.1177/1470320313512390

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Genetic variants of ACE (Insertion/Deletion) and AGT (M268T) genes in patients with diabetes and nephropathy.

Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Jun 2014

Shaikh Rozeena, Shahid Syed M, Mansoor Qaisar, Ismail Muhammad, Azhar Abid

Abstract excerpt

INTRODUCTION: Diabetes mellitus (DM) has been a growing epidemic worldwide and poses a major socio-economic challenge. The leading cause of DM death is nephropathy due to end-stage renal disease (ESRD). This study aims to identify the possible association of I/D variants of the ACE gene and M268T (rs699) of the AGT gene of renin-angiotensin-aldosterone system (RAAS). MATERIALS AND METHODS: Study subjects include...

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PMID: 24737640
DOI: 10.1177/1470320313512390

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