Article
Lack of association between the insertion/deletion polymorphism of the angiotensin-converting-enzyme gene and diabetic nephropathy in IDDM patients.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme - 1 May 1998
Pfohl M, Frost D, Koch M, Clemens P, Patzies A, Schmülling R M, Beischer W, Häring H U
Abstract excerpt
The insertion/deletion (I/D) polymorphism of the angiotensin-converting-enzyme (ACE) gene has been reported to be associated with diabetic nephropathy in IDDM. We studied the relationship between this polymorphism and diabetic nephropathy in 210 IDDM patients. Their DNA was analyzed by polymerase chain reaction to type for the presence (I) or absence (D) of the 287 bp fragment in intron 16 of the ACE gene. The...
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