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Article

ACE variants interact with the RAS pathway to confer risk and protection against type 2 diabetic nephropathy.

DNA and cell biology - 1 Mar 2009

Ahluwalia Tarunveer Singh, Ahuja Monica, Rai Taranjit Singh, Kohli Harbir Singh, Bhansali Anil, Sud Kamal, Khullar Madhu

Abstract excerpt

Genetic predisposition has been proposed to be a major determinant in the development of renal complications of diabetes. Among candidate genes examined for susceptibility to diabetic nephropathy, angiotensin-converting enzyme (ACE) gene has been found to be associated with pathogenesis and progression of diabetic nephropathy. However, the role of other renin-angiotensin system (RAS) polymorphisms and their...

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Source

Identifiers

PMID: 19108684
DOI: 10.1089/dna.2008.0810

Genes

ACE
AGT
AGTR1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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