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Article

Multidrug resistance-related protein 2 genotype of the donor affects kidney graft function.

Pharmacogenetics and genomics - 1 Apr 2009

Grisk Olaf, Steinbach Antje C, Ciecholewski Sabine, Schlüter Torsten, Klöting Ingrid, Schmidt Helmut, Dazert Eike, Schaeffeler Elke, Steil Leif, Gauer Stefan, Jedlitschky Gabriele, Schwab Matthias, Geisslinger Gerd, Hauser Ingeborg A, Völker Uwe, Kroemer Heyo K, Rettig Rainer

Abstract excerpt

OBJECTIVES: We tested the effect of kidney-specific multidrug resistance-related protein (MRP2, ABCC2) deficiency on renal organic solute disposition as well as on renal protein and gene expression. Furthermore, we investigated whether a particular kidney donor ABCC2 genotype is associated with delayed graft function in patients. METHODS: A new MRP2-deficient rat strain was established. Renal...

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Source

Identifiers

PMID: 19214140
DOI: 10.1097/FPC.0b013e328328d4e9

Genes

ABCC2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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