A Functional SNP in BNC2 Is Associated with Adolescent Idiopathic Scoliosis.

doi:10.1016/j.ajhg.2015.06.012

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Article

A Functional SNP in BNC2 Is Associated with Adolescent Idiopathic Scoliosis.

American journal of human genetics - 6 Aug 2015

Ogura Yoji, Kou Ikuyo, Miura Shigenori, Takahashi Atsushi, Xu Leilei, Takeda Kazuki, Takahashi Yohei, Kono Katsuki, Kawakami Noriaki, Uno Koki, Ito Manabu, Minami Shohei, Yonezawa Ikuho, Yanagida Haruhisa, Taneichi Hiroshi, Zhu Zezhang, Tsuji Taichi, Suzuki Teppei, Sudo Hideki, Kotani Toshiaki, Watanabe Kota, Hosogane Naobumi, Okada Eijiro, Iida Aritoshi, Nakajima Masahiro, Sudo Akihiro, Chiba Kazuhiro, Hiraki Yuji, Toyama Yoshiaki, Qiu Yong, Shukunami Chisa, Kamatani Yoichiro, Kubo Michiaki, Matsumoto Morio, Ikegawa Shiro

Abstract excerpt

Adolescent idiopathic scoliosis (AIS) is the most common spinal deformity. We previously conducted a genome-wide association study (GWAS) and detected two loci associated with AIS. To identify additional loci, we extended our GWAS by increasing the number of cohorts (2,109 affected subjects and 1...

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Identifiers

PMID: 26211971
DOI: 10.1016/j.ajhg.2015.06.012
PMCID: PMC4573260

Genes

BNC2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-26211971-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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