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Article

Genetic variant of BNC2 gene is functionally associated with adolescent idiopathic scoliosis in Chinese population.

Molecular genetics and genomics : MGG - 1 Aug 2017

Xu Leilei, Xia Chao, Qin Xiaodong, Sun Weixiang, Tang Nelson Leung-Sang, Qiu Yong, Cheng Jack Chun-Yiu, Zhu Zezhang

Abstract excerpt

Adolescent idiopathic scoliosis (AIS) is a structural curvature of the spine that was estimated to affect millions of children worldwide. Recent study shows that the functional variant rs10738445 could add to the risk of AIS through the regulation of BNC2 gene. This study aims to investigate whether the rs10738445 of BNC2 gene is a functional susceptible locus for AIS in the Chinese population and to further...

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Source

Identifiers

PMID: 28342042
DOI: 10.1007/s00438-017-1315-3

Genes

BNC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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