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Article

The role of viral and host genetics in natural history and treatment of chronic HCV infection.

Best practice & research. Clinical gastroenterology - 1 Aug 2012

Doyle Joseph S, Hellard Margaret E, Thompson Alexander J

Abstract excerpt

Understanding of the natural history and treatment responsiveness of chronic hepatitis C virus (HCV) infection has evolved rapidly in recent years. Advances in HCV molecular virology and host genetics can now better predict spontaneous clearance and treatment outcomes. HCV genotype is the most important viral factor predicting interferon-α treatment responsiveness; HCV-1 subtype is emerging as a key determinant...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23199501
DOI: 10.1016/j.bpg.2012.09.004

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