Article
CXCR3 Polymorphism and Expression Associate with Spontaneous Preterm Birth.
Journal of immunology (Baltimore, Md. : 1950) - 1 Sept 2015
Karjalainen Minna K, Ojaniemi Marja, Haapalainen Antti M, Mahlman Mari, Salminen Annamari, Huusko Johanna M, Määttä Tomi A, Kaukola Tuula, Anttonen Julia, Ulvila Johanna, Haataja Ritva, Teramo Kari, Kingsmore Stephen F, Palotie Aarno, Muglia Louis J, Rämet Mika, Hallman Mikko
Abstract excerpt
Spontaneous preterm birth (SPTB) is a major factor associating with deaths and with lowered quality of life in humans. Environmental and genetic factors influence the susceptibility. Previously, by analyzing families with recurrent SPTB in linkage analysis, we identified a linkage peak close to the gene encoding CXCR3. Present objectives were to investigate the association of CXCR3 with SPTB in Finnish mothers (n...
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