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Article

Association of maternal VDR and VDBP gene polymorphisms with spontaneous preterm birth risks: a nested case-control study in China.

BMC pregnancy and childbirth - 28 Nov 2025

Li Nana, Zhou Mengling, Li Lu, Li Yuting, Wang Meixian, Deng Ying, Wang Yanping, Zhu Jun, Zhou Shu, Yu Ping

Abstract excerpt

BACKGROUND: The impact of vitamin D on spontaneous preterm birth (SPTB) is still not well understood. This study aimed to explore the relationship between maternal vitamin D receptor (VDR) and vitamin D-binding protein (VDBP) gene polymorphisms, as well as gene-gene interactions, and their potential association with the risks of SPTB. METHODS: A nested case-control study involving 200 pregnant women with SPTB and...

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Source

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Identifiers

PMID: 41316006
DOI: 10.1186/s12884-025-08519-7
PMCID: PMC12763941

Genes

SPTB
VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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