Article
Association between trefoil factor 3 gene variants and idiopathic recurrent spontaneous abortion.
Reproductive biomedicine online - 1 Dec 2014
Haroun Sally, Altmäe Signe, Karypidis Helena, Kuningas Maris, Landgren Britt-Marie, Akerud Helena, Skjöldebrand-Sparre Lottie, Hosseini Frida, Bremme Katarina, Sundström-Poromaa Inger, Stavreus-Evers Anneli
Abstract excerpt
Trefoil factor 3 (TFF3) gene is an inflammatory mediator expressed in human endometrium during the window of implantation. The aim of this study was to evaluate the possible genetic association of TFF3 variants in recurrent spontaneous abortion. Women with a history of recurrent spontaneous abortion (n = 164) and healthy pregnant women (n = 143) were genotyped for five TFF3 polymorphisms (rs225439 G/A, rs533093...
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