Transcriptomics reveals preterm birth risk: identification and validation of key genes in monocytes

Abstract excerpt

BACKGROUND: Preterm birth (PTB) is a leading cause of neonatal mortality and long-term disability worldwide. However, the molecular mechanisms underlying PTB remain incompletely understood, and the etiology of many PTB cases is still largely unexplained. Due to their close association with PTB, monocytes serve as an ideal matrix for identifying peripheral biomarkers predictive of preterm birth risk. OBJECTIVE:...

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