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MYC Levels Regulate Metastatic Heterogeneity in Pancreatic Adenocarcinoma

22 Sept 2021

Abstract excerpt

Abstract The degree of metastatic disease varies widely among patients with cancer and affects clinical outcomes. However, the biological and functional differences that drive the extent of metastasis are poorly understood. We analyzed primary tumors and paired metastases using a multifluorescent lineage-labeled mouse model of pancreatic ductal adenocarcinoma (PDAC)—a tumor type in which most patients present...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34551968
DOI: 10.1158/2159-8290.cd-20-1826

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