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Article

Transcriptional regulation of the VEGF gene in dependence of individual genomic variations.

Cytokine - 1 Dec 2015

Metzger Carmen S, Koutsimpelas Dimitrios, Brieger Juergen

Abstract excerpt

Overexpression of the vascular endothelial growth factor (VEGF) gene has been associated with advanced stage and poor survival in several cancers. The majority of disease-associated VEGF-single nucleotide polymorphisms (SNPs) locate within regulatory regions. Therefore, an influence of SNPs located in the promoter/5'-untranslated region (5'UTR) on transcription factor binding (TFB) and gene expression seems...

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Source

Identifiers

PMID: 26209503
DOI: 10.1016/j.cyto.2015.07.015

Genes

MZF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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