Potential Impact of Vascular Endothelial Growth Factor Gene Variation (-2578C>A) on Breast Cancer Susceptibility in Saudi Arabia: a Case-Control Study

doi:10.22034/APJCP.2018.19.4.1135

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Potential Impact of Vascular Endothelial Growth Factor Gene Variation (-2578C>A) on Breast Cancer Susceptibility in Saudi Arabia: a Case-Control Study

Asian Pacific journal of cancer prevention : APJCP - 27 Apr 2018

Al Balawi Ibrahim Abdullah, Mir Rashid, Abu-Duhier F M

Abstract excerpt

Aim: VEGF gene polymorphisms can induce either increase or inhibition of VEGF secretion, with altered promoter activity. The VEGF rs699947 SNP is located in the promoter region and is associated with susceptibility to breast carcinoma development. Here, we investigated the association of the -2578C>A polymorphism in the VEGF gene with breast cancer risk in Saudi women. Methodology: Genotyping of the VEGF-gene...

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Identifiers

PMID: 29699375
DOI: 10.22034/APJCP.2018.19.4.1135
PMCID: PMC6031782

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